The letters N, I, C, E can be unscrambled into 5 words, including one anagram that uses every letter: CINE. The highest-scoring common word is ICE (5 points).
Definitions from WordNet 3.1, Princeton University.
NICE is valid in the ENABLE word list used by many word game apps. In everyday English it is common: used every day in ordinary English. Points are face values only, without board bonuses.
Words that use all 4 letters exactly once.
5 words, longest first. Faded words are valid in word games but rarely used in everyday English.
Words you can make with all the letters of NICE plus one more. Handy when there is a free tile on the board.
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